We provide our clients with a translational pharmacological approach which gives quantifiable and visible evidence of disease progression and treatment, drug efficacy and safety in their animal models.
X-rays and Contact Radiography
X-ray technology is the oldest and most commonly used form of medical imaging and remains an important tool for the diagnosis of many osteoarticular disorders. We perform Standard X-rays as well contact X-rays (Faxitron).
In Vivo Computed Tomography
Computed Tomography (CT) is an X-ray based technique imaging live animals. This technique is usually used to assess a surgical technique, to check the position of a medical device or to follow disease progression while a study is ongoing. At Biograding Solutions we offer in vivo CT for all species from small to large animals.
Micro-Computed Tomography
Micro-Computed Tomography is an X-ray transmission imaging technique. It creates cross-sections of the physical samples that can be used to recreate a virtual model (3D model) without destroying the original object. This is useful for non-destructively visualising and analysing the internal structure of materials.
3D reconstruction of a fused dog spine
In Vivo Computed Tomography
Computed Tomography (CT) is an X-ray based technique imaging live animals. This technique is usually used to assess a surgical technique, to check the position of a medical device or to follow disease progression while a study is ongoing. At Biograding Solutions we offer in vivo CT for all species from small to large animals.
Micro-Computed Tomography
Micro-Computed Tomography is an X-ray transmission imaging technique. It creates cross-sections of the physical samples that can be used to recreate a virtual model (3D model) without destroying the original object. This is useful for non-destructively visualising and analysing the internal structure of materials.
2D and 3D images of a condyle defect in a sheep knee.
Magnetic Resonance Imaging (MRI)
MRI is a medical imaging technique used to obtain pictures of the anatomy and the physiological processes of the body in both health and disease situation. At Biograding Solutions, we use MRI to assess cartilage repair or disc degeneration both in vivo and ex vivo.
In Vivo Bioluminescence Imaging
In vivo bioluminescent imaging (BLI) is a versatile and sensitive tool that is based on detection of light emission from cells. Optical imaging by bioluminescence allows a low-cost, non-invasive, and real-time analysis of disease processes in living organisms. Bioluminescence is used to track tumour cells, bacterial and viral infections, gene expression, and treatment response. At Biograding Solutions, bioluminescence can be used to visualise the progression of bone cancer in spine or tibia of rodents.
Prostate cancer cells were injected directly in the tibia of nude mice. Tumour burden was assessed by bioluminescence at D0, D20 and D42 after tumour cells injection.
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Customers Around The World
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Countries Served
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Due Diligence
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Preclinical Histology Slides Performed
