Preclinical Pain Models

Preclinical models of inflammatory and rheumatoid arthritis pain involve the injection of immunogenic or non-immunogenic adjuvants in the joints or in the systemic system.
Neuropathic pain models involve partial nerve injury such as ligature of the spinal or sciatic nerves.

Pain Models:

● Post-Surgical Pain Models
● Visceral Pain
● Acute and Chemogenic Pain
● Inflammatory Pain
● Neuropathic Pain
● Bone and Joint pain

Endpoints assessment of the quality of life in a Preclinical Model of Arthritis:

● Paw Withdrawal Test (Latency and Duration)
● Static Weight-Bearing
● Validated Pain Scores for Several Animal Species
● Video-Monitoring of Animals (Behavioural Studies)
● Algometry
● Electrophysiology

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